Yi Chen

TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling

Rongxuan Zhu, Olivier Gires, Jun Liu et al. · Nature Communications · 2019 · 190 citations · Full text

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer

Hanlin Zeng, Jia Qu, Nan Jin et al. · Cancer Cell · 2016 · 163 citations

Breast Oncology, Medicine, Feedback Activation +8

Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance

Tao Zhang, Rong Qu, Shingpan Chan et al. · Molecular Cancer · 2020 · 139 citations · Full text

G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin

Ya‐Fang Wang, Jie Zhang, Yi Su et al. · Nature Communications · 2017 · 121 citations · Full text

Synthesis and c-Met Kinase Inhibition of 3,5-Disubstituted and 3,5,7-Trisubstituted Quinolines: Identification of 3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7- (trifluoromethyl)quinoline as a Novel Anticancer Agent

Yuanxiang Wang, Jing Ai, Ying Wang et al. · Journal of Medicinal Chemistry · 2011 · 108 citations · Full text

3,5,7-Trisubstituted Quinolines, Compound 21B, Pharmacotherapy +18