Dual mRNA co-delivery for in situ generation of phagocytosis-enhanced CAR macrophages augments hepatocellular carcinoma immunotherapy

Zhenmei Yang, Ying Liu, Kun Zhao, +14

Journal of Controlled Release

Situ GenerationCancer ImmunosurveillanceImmunologyDual Mrna Co-deliveryCancer Vaccines +6

Quercetin Has Antimetastatic Effects on Gastric Cancer Cells via the Interruption of uPA/uPAR Function by Modulating NF-κb, PKC-δ, ERK1/2, and AMPKα

Li Hai, Chen Chen

Integrative Cancer Therapies

Gastric Cancer CellsChemoprevention StrategyPathologyCancer MetastasisCancer Biology +17

Inhaled mRNA Nanoformulation with Biogenic Ribosomal Protein Reverses Established Pulmonary Fibrosis in a Bleomycin‐Induced Murine Model

Rui Zhang, Weiqiang Jing, Chen Chen, +24

Advanced Materials

EngineeringInflammatory Lung DiseaseLung InflammationMolecular BiologyPulmonary Alveolar Proteinosis +24

Plant Polyphenols and Oxidative Metabolites of the Herbal Alkenylbenzene Methyleugenol Suppress Histone Deacetylase Activity in Human Colon Carcinoma Cells

Isabel Anna Maria Groh, Chen Chen, Claudia M. Lüske, +2

Journal of Nutrition and Metabolism

Convection-enhanced delivery of nanoencapsulated gene locoregionally yielding ErbB2/Her2-specific CAR-macrophages for brainstem glioma immunotherapy

Lin Gao, Chongdeng Shi, Zhenmei Yang, +9

Journal of Nanobiotechnology

Fabricating High-Resolution Metal Pattern with Inkjet Printed Water-Soluble Sacrificial Layer

Jiazhen Sun, Yang Li, Guangping Liu, +5

ACS Applied Materials & Interfaces

Materials ScienceChemical EngineeringEngineeringBeam LithographyFlexible Electronics +12

Design, synthesis and biological evaluation of quinoline derivatives as HDAC class I inhibitors

Chen Chen, Xuben Hou, Guohua Wang, +4

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryDerivative (Chemistry)BiochemistryMedicine +8

Combined lethal toxicity, biochemical responses, and gene expression variations induced by tebuconazole, bifenthrin and their mixture in zebrafish (Danio rerio)

Yanhua Wang, Chen Chen, Guiling Yang, +5

Ecotoxicology and Environmental Safety

Discovery of DNA-Targeting HDAC Inhibitors with Potent Antitumor Efficacy In Vivo That Trigger Antitumor Immunity

Chen Chen, Xue Li, Huajun Zhao, +6

Journal of Medicinal Chemistry

Design, synthesis and preliminary bioactivity evaluations of 8-hydroxyquinoline derivatives as matrix metalloproteinase (MMP) inhibitors

Chen Chen, Xinying Yang, Hao Fang, +1

European Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryMatrix MetalloproteinaseMedicineNatural Sciences +7