Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

Haibo Zhang, Josef Penninger, Yimin Li, +2

Intensive Care Medicine

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

Vanessa Monteil, Hyesoo Kwon, Patricia Prado, +15

Cell

Human recombinant soluble ACE2 in severe COVID-19

Alexander Zoufaly, Marko Poglitsch, Judith H. Aberle, +17

The Lancet Respiratory Medicine

Covid-19 PandemicImmunologySevere Covid-19VirologyCovid-19 Epidemiology +2

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

Nepton Soltani, Hongmin Qiu, Mila Aleksic, +13

Proceedings of the National Academy of Sciences

Correlation of serial blood lactate levels to organ failure and mortality after trauma

Panagiotis Manikis, S. Jankowski, Haibo Zhang, +2

The American Journal of Emergency Medicine

Trauma ResuscitationHeart FailureTraumatologyAcute Kidney InjuryMedicine +1

Acute phase response in zebrafish upon Aeromonas salmonicida and Staphylococcus aureus infection: Striking similarities and obvious differences with mammals

Bin Lin, Shangwu Chen, Zhen Cao, +7

Molecular Immunology

BiologyAcute Phase ResponsePathogen TransmissionAeromonas SalmonicidaPathogenesis +7

Acute respiratory distress syndrome: new definition, current and future therapeutic options.

Vito Fanelli, Aikaterini Vlachou, Shirin Ghannadian, +3

PubMed

Acute Lung InjuryAsthmaPulmonary CareRespiratory Distress Syndrome (Pulmonary Critical Care)Acute Respiratory Distress Syndrome +17

JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality

Justin Stebbing, Ginés Sánchez Nievas, Marco Falcone, +46

Science Advances

ImmunologyAntiviral DrugInflammationAntiviral Drug DevelopmentJak Inhibition +15

Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia—A review

Marcus J. Schultz, Jack J. Haitsma, Haibo Zhang, +1

Critical Care Medicine

Pressure–Time Curve Predicts Minimally Injurious Ventilatory Strategy in an Isolated Rat Lung Model

V. Marco Ranieri, Haibo Zhang, Luciana Mascia, +8

Anesthesiology