The location and structure of double-strand DNA breaks induced during yeast meiosis: evidence for a covalently linked DNA-protein intermediate.

Jia Liu, T C Wu, Michael Lichten

The EMBO Journal

ChromatinGenome InstabilityDna-protein IntermediateChromatin StructureCell Division +13

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2

Lu Qiao, Jia Liu, Shuai Zhao, +47

Immunity

InflammationCytokineImmunologyImmunologic MechanismHumoral Immunity +7

A membrane-associated MHC-I inhibitory axis for cancer immune evasion

Xufeng Chen, Lu Qiao, Hua Zhou, +22

Cell

Immune EvasionCancer Immune EvasionCancer ImmunosurveillanceImmunologyTumor Immunity +4

Targeting IL-21 to tumor-reactive T cells enhances memory T cell responses and anti-PD-1 antibody therapy

Ying Li, Yanni Cong, Mingming Jia, +10

Nature Communications

Involvement of the mitochondrial pathway and Bim/Bcl-2 balance in dihydroartemisinin-induced apoptosis in human breast cancer in vitro

Haiting Mao, Hongtao Gu, Xun Qu, +5

International Journal of Molecular Medicine

Breast OncologyChemoprevention StrategyApoptosisCell DeathHuman Breast Cancer +22

Cyclometalated platinum(ii) complexes as topoisomerase IIα poisons

Jia Liu, Chung‐Hang Leung, Andy Lok‐Fung Chow, +3

Chemical Communications

Inorganic ChemistryInduces CancerChemoprevention StrategyBiochemistryTopoisomerase Iiα Poisons +10

Mechanical activation of spike fosters SARS-CoV-2 viral infection

Wei Hu, Yong Zhang, Panyu Fei, +17

Cell Research

Targeted Gene Knock In and Sequence Modulation Mediated by a Psoralen-linked Triplex-forming Oligonucleotide*

Alokes Majumdar, Parameswary A. Muniandy, Jia Liu, +4

Journal of Biological Chemistry

Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2

Shion A. Lim, Josef A. Gramespacher, Katarina Pance, +11

mAbs

VaccinationNon-neutralizing Rbd AntibodiesBispecific Vh/fabVaccine TargetImmunology +13

Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function

John L. Silberstein, Jasper Du, Kun‐Wei Chan, +14

Proceedings of the National Academy of Sciences

ImmunologyImmune RegulationMolecular BiologyLag-3 Dimer FormationImmunologic Mechanism +21