Concepedia

Yu Chen

YC

Statistics

Publications

88

Citations

6.7K

H-Index

40

Active since

2000

Affiliations

University of South Florida(Current)

University of California, San Francisco

University of Arizona

Rutgers, The State University of New Jersey

Florida College

Yu Chen is an author at University of South Florida specializing in life sciences, structural biology, and drug discovery.

Publications per year

2000–2025

88

Publications

88

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

Chunlong Ma, M. Sacco, Brett L. Hurst et al. · Cell Research · 2020 · 885 citations · Full text

Pharmacy, Infectious Diseases, Medicinal Chemistry +17

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M <sup>pro</sup> and cathepsin L

M. Sacco, Chunlong Ma, Panagiotis Lagarias et al. · Science Advances · 2020 · 399 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +14

Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins

Yongna Xing, Yanhui Xu, Yu Chen et al. · Cell · 2006 · 338 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir

Yanmei Hu, Eric M. Lewandowski, Haozhou Tan et al. · ACS Central Science · 2023 · 306 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Molecular docking and ligand specificity in fragment-based inhibitor discovery

Yu Chen, Brian K. Shoichet · Nature Chemical Biology · 2009 · 249 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

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