Xu Chen

Epigenetic modulation of Drp1-mediated mitochondrial fission by inhibition of S-adenosylhomocysteine hydrolase promotes vascular senescence and atherosclerosis

Yiran You, Xu Chen, Yu Chen et al. · Redox Biology · 2023 · 78 citations · Full text

Veterinary Medicine, Cell Biology, Molecular Biology +17

Activity-balanced GLP-1/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates

Yuanyuan Zhang, Xinyu Zhao, Xiaona Dong et al. · Cell Metabolism · 2023 · 47 citations

Medicine, Endocrinology, Pharmacology +14

Cetirizine dihydrochloride loaded microparticles design using ionotropic cross-linked chitosan nanoparticles by spray-drying method

Feng‐Qian Li, Rui-Rui Ji, Xu Chen et al. · Archives of Pharmacal Research · 2010 · 38 citations

Pharmacy, Materials Science, Pharmaceutics +14

Cathepsin L-containing exosomes from α-synuclein-activated microglia induce neurotoxicity through the P2X7 receptor

Tianfang Jiang, Chuanying Xu, Shane Gao et al. · npj Parkinson s Disease · 2022 · 33 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Higher S-adenosylhomocysteine and lower ratio of S-adenosylmethionine to S-adenosylhomocysteine were more closely associated with increased risk of subclinical atherosclerosis than homocysteine

Jinghe Xiao, Yiran You, Xu Chen et al. · Frontiers in Nutrition · 2022 · 29 citations · Full text

Life Sciences, Biochemistry, Nutrition +13