Yan Chen

Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins

Hua Huang, Fang Sun, David M. Owen et al. · Proceedings of the National Academy of Sciences · 2007 · 507 citations · Full text

Viral Replication, Immunology, Viral Hepatitis +17

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

Shu‐Yong Lin, Terytty Yang Li, Qing Liu et al. · Science · 2012 · 346 citations

Cell Autophagy, Mitophagy, Energy Homeostasis +12

Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing

Junjie Hu, Lele Zhang, Haoran Xia et al. · Genome Medicine · 2023 · 342 citations · Full text

AXL Mediates Resistance to PI3Kα Inhibition by Activating the EGFR/PKC/mTOR Axis in Head and Neck and Esophageal Squamous Cell Carcinomas

Moshe Elkabets, Evangelos Pazarentzos, Dejan Juric et al. · Cancer Cell · 2015 · 331 citations · Full text

Oncology, Pi3kα Inhibition, Signaling Pathway +13

Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

Wei Shi, Dan Xiao, Lin Wang et al. · Cell Death and Disease · 2012 · 296 citations · Full text