Yan Chen

Preclinical Development of MGC018, a Duocarmycin-based Antibody–drug Conjugate Targeting B7-H3 for Solid Cancer

Juniper A. Scribner, Jennifer G. Brown, Thomas Son et al. · Molecular Cancer Therapeutics · 2020 · 159 citations

Medicine, Medicinal Chemistry, Oncology +15

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception

Shen Yue, Liu-Ya Tang, Ying Tang et al. · eLife · 2014 · 96 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Inhibition of MDM2 Promotes Antitumor Responses in p53 Wild-Type Cancer Cells through Their Interaction with the Immune and Stromal Microenvironment

Hui Qin Wang, Iain J. Mulford, Fiona A. Sharp et al. · Cancer Research · 2021 · 62 citations · Full text

Medicine, Immunology, Oncology +17

Significant pharmacokinetic differences of berberine are attributable to variations in gut microbiota between Africans and Chinese

Raphael N. Alolga, Yong Fan, Zhuo Chen et al. · Scientific Reports · 2016 · 55 citations · Full text

Life Sciences, Microbiology, Pharmacokinetics +17

Ursolic acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in non‐small‐cell lung carcinoma harbouring EGFR T790M mutations

Kaiyong Yang, Yan Chen, Jiaqian Zhou et al. · British Journal of Pharmacology · 2019 · 51 citations · Full text

Medicine, Oncology, Pharmacology +17