Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing

Ashley Maynard, Caroline E. McCoach, Julia Rotow, +40

Cell

Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers

Collin M. Blakely, Thomas B.K. Watkins, Wei Wu, +26

Nature Genetics

Co-occurring Genetic AlterationsOncologySomatic VariantMedicineGenetics +8

Microarray Analysis Reveals Glucocorticoid-Regulated Survival Genes That Are Associated With Inhibition of Apoptosis in Breast Epithelial Cells

Wei Wu, Shamita Chaudhuri, Deanna R. Brickley, +3

Cancer Research

Breast OncologyApoptosisImmunologyCell DeathGlucocorticoid +17

Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution

Dian Yang, Matthew G. Jones, Santiago Naranjo, +20

Cell

Lineage PlasticityCell LineageDevelopmental BiologyTumor HeterogeneitySingle Cell Sequencing +13

Concurrent <i>CIC</i> mutations, <i>IDH</i> mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers

Stephen Yip, Yaron S.N. Butterfield, Olena Morozova, +36

The Journal of Pathology

Cancer PathologyPathologyOther CancersHigh-grade GliomasGlioma +18

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma

Yuxiang Wang, Jie Yang, Aaron T. Wild, +8

Nature Communications

Glucocorticoid Receptor-induced MAPK Phosphatase-1 (MPK-1) Expression Inhibits Paclitaxel-associated MAPK Activation and Contributes to Breast Cancer Cell Survival

Wei Wu, Travis Pew, Min Zou, +2

Journal of Biological Chemistry

Breast OncologyApoptosisCell DeathGlucocorticoid ReceptorCancer Biology +15

Inactivation of Capicua drives cancer metastasis

Ross A. Okimoto, Frank Breitenbuecher, Victor Olivas, +16

Nature Genetics

Tumor BiologyMedicineCancer BiologyCell BiologyTumor Microenvironment +1

Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma

Wei Cao, Hayan Lee, Wei Wu, +27

Nature Communications

BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis

Kai Huang, Katelyn O’Neill, Jian Li, +8

Cell Research

MedicineApoptosisCell DeathBh3-only ProteinsCancer Biology +2