The TOR pathway interacts with the insulin signaling pathway to regulate <i>C. elegans</i> larval development, metabolism and life span

Kailiang Jia, Di Chen, Donald L Riddle

Development

Inhibition of mRNA translation extends lifespan in <i>Caenorhabditis elegans</i>

Kally Z. Pan, Julia E. Palter, Aric N. Rogers, +4

Aging Cell

HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans

Di Chen, Emma Thomas, Pankaj Kapahi

PLoS Genetics

Anti-agingMolecular RegulationGeneticsEr StressBiogerontology +14

Longevity determined by developmental arrest genes in <i>Caenorhabditis elegans</i>

Di Chen, Kally Z. Pan, Julia E. Palter, +1

Aging Cell

BiologyLifespan ExtensionDevelopmental BiologyAgingAnti-aging +12

Life Span Extension via eIF4G Inhibition Is Mediated by Posttranscriptional Remodeling of Stress Response Gene Expression in C. elegans

Aric N. Rogers, Di Chen, Gawain McColl, +7

Cell Metabolism

Transcriptional RegulationDevelopmental BiologySignaling PathwayGene RegulationEif4g Inhibition Is +5

Germline Signaling Mediates the Synergistically Prolonged Longevity Produced by Double Mutations in daf-2 and rsks-1 in C. elegans

Di Chen, Patrick Wai-Lun Li, Benjamin A. Goldstein, +6

Cell Reports

GeneticsMolecular GeneticsSignaling PathwayLongevityGermline Signaling +18

A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species

Russell Bell, Alan Hubbard, Rakesh Chettier, +7

PLoS Genetics

Protein Interaction NetworkAgingGeneticsBiogerontologyLongevity +18

Construction of a germline-specific RNAi tool in C. elegans

Lina Zou, Di Wu, Xiao Zang, +3

Scientific Reports

Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity

Jianfeng Lan, Jarod Rollins, Xiao Zang, +8

Cell Reports

A SNP of bacterial blc disturbs gut lysophospholipid homeostasis and induces inflammation through epithelial barrier disruption

Dayuan Zou, Jingwen Pei, Jianfeng Lan, +12

EBioMedicine