Li Li

Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPα expression

Rui Zheng, Alan D. Friedman, Mark J. Levis et al. · Blood · 2003 · 154 citations

Life Sciences, Genetics, Molecular Genetics +16

Internal tandem duplications of the FLT3 gene are present in leukemia stem cells

Mark J. Levis, Kathleen M. Murphy, Rosalyn Pham et al. · Blood · 2005 · 147 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model

Li Li, Obdulio Piloto, Ho Bao Nguyen et al. · Blood · 2008 · 127 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation

Ruiqi Zhu, Li Li, Bao Nguyen et al. · Signal Transduction and Targeted Therapy · 2021 · 106 citations · Full text

Medicine, Oncology, Pharmacology +13

FLT3-ITD Knockin Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to Myeloproliferative Neoplasm

S. Haihua Chu, Diane Heiser, Li Li et al. · Cell stem cell · 2012 · 89 citations · Full text

Medicine, Genetics, Hematology +12