Yang Zhang

Oxygen‐Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF‐<i>κ</i>B Pathways

Chencheng Feng, Yang Zhang, Minghui Yang et al. · Oxidative Medicine and Cellular Longevity · 2017 · 70 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Lactic acid promotes nucleus pulposus cell senescence and corresponding intervertebral disc degeneration via interacting with Akt

Yuyao Zhang, Libangxi Liu, Yuhan Qi et al. · Cellular and Molecular Life Sciences · 2024 · 63 citations · Full text

Life Sciences, Biochemistry, Cell Biology +11

Mitochondrial DNA induces nucleus pulposus cell pyroptosis via the TLR9-NF-κB-NLRP3 axis

Lü Peng, Huayong Zheng, Hao Meng et al. · Journal of Translational Medicine · 2023 · 57 citations · Full text

Life Sciences, Cell Biology, Immunology +15

Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells

Chencheng Feng, Minghui Yang, Yang Zhang et al. · International Journal of Molecular Medicine · 2018 · 54 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Injectable nanostructured colloidal gels resembling native nucleus pulposus as carriers of mesenchymal stem cells for the repair of degenerated intervertebral discs

Yu Wang, Yang Zhang, Kaiwen Chen et al. · Materials Science and Engineering C · 2021 · 50 citations

Engineering, Bioengineering, Biomedical Engineering +17