PML/RARα Targets Promoter Regions Containing PU.1 Consensus and RARE Half Sites in Acute Promyelocytic Leukemia

Kankan Wang, Ping Wang, Jiantao Shi, +15

Cancer Cell

Hematological MalignancyTranscriptional RegulationMixed-phenotype Acute LeukemiaPathologyRare Half Sites +5

Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration

Ning Xiao, Hui Li, Jian Luo, +4

Biochemical Journal

ImmunologyImmune RegulationInnate ImmunityImmune SystemCancer Biology +22

The Ubiquitination of RagA GTPase by RNF152 Negatively Regulates mTORC1 Activation

Lu Deng, Cong Jiang, Lei Chen, +14

Molecular Cell

Signal TransductionSignaling PathwayCell RegulationMolecular RegulationReceptor Tyrosine Kinase +7

Ubiquitination of Rheb governs growth factor-induced mTORC1 activation

Lu Deng, Lei Chen, Linlin Zhao, +13

Cell Research

Genome-wide transcriptome analysis of genes involved in flavonoid biosynthesis between red and white strains of Magnolia sprengeri pamp

Shouguo Shi, Mei Yang, Min Zhang, +3

BMC Genomics

OTUB1 protein suppresses mTOR complex 1 (mTORC1) activity by deubiquitinating the mTORC1 inhibitor DEPTOR

Linlin Zhao, Xinbo Wang, Yue Yu, +9

Journal of Biological Chemistry

Molecular PhysiologySignal TransductionOtub1 ProteinReceptor Tyrosine KinaseMolecular Biology +5

Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines

Limin Li, Xiaobo Zhou, Wai Ki Ching, +1

BMC Bioinformatics

Randomized double-blind clinical trial of Moluodan (摩罗丹) for the treatment of chronic atrophic gastritis with dysplasia

Xudong Tang, Liya Zhou, Shutian Zhang, +10

Chinese Journal of Integrative Medicine

Chronic Atrophic GastritisGastroenterologyDouble-blind Clinical TrialClinical GastroenterologySurgery +1

Identification of sequence polymorphisms in the D-loop region of mitochondrial DNA as a risk factor for lung cancer

Cuimin Ding, Ruijuan Li, Ping Wang, +3

Mitochondrial DNA

LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation

Rui Cai, Ping Wang, Xin Zhao, +6

Journal of Translational Medicine