Chen Wang

RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling

Ann Durbin, Chen Wang, Joseph Marcotrigiano et al. · mBio · 2016 · 231 citations · Full text

STING inhibitors target the cyclic dinucleotide binding pocket

Ze Hong, Jiahao Mei, Chenhui Li et al. · Proceedings of the National Academy of Sciences · 2021 · 223 citations · Full text

RIG-I Uses an ATPase-Powered Translocation-Throttling Mechanism for Kinetic Proofreading of RNAs and Oligomerization

Swapnil C. Devarkar, Brandon Schweibenz, Chen Wang et al. · Molecular Cell · 2018 · 82 citations · Full text

Rna Processing, Natural Sciences, Rna Structure Prediction +8

Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening

Joschka Willemsen, Oliver Wicht, Julia Wolanski et al. · Molecular Cell · 2017 · 60 citations · Full text

Phosphorylation-dependent Feedback Inhibition, Signal Transduction, Signaling Pathway +10

HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity

Jie Zheng, Chen Wang, Mi Ra Chang et al. · Nature Communications · 2018 · 36 citations · Full text