NLRP3 inflammasome induces CD4+ T cell loss in chronically HIV-1–infected patients

Chao Zhang, Jin‐Wen Song, Hui-Huang Huang, +18

Journal of Clinical Investigation

Nlrp3-dependent PyroptosisImmunologyPathologyCell DeathCd4 T Cell Responses +19

Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis

Qin Chen, Xingguang Liu, Dingyu Wang, +10

Frontiers in Cell and Developmental Biology

ApoptosisImmunologyImmune RegulationCell DeathInnate Immunity +16

Patulin induces pyroptosis through the autophagic-inflammasomal pathway in liver

Qian Chu, Shaopeng Wang, Liping Jiang, +10

Food and Chemical Toxicology

Cell AutophagyMitophagyHepatologyPatulin Induces PyroptosisLiver Physiology +8

Syringaresinol protects against diabetic nephropathy by inhibiting pyroptosis via NRF2-mediated antioxidant pathway

Guangru Li, Chang Liu, Lei Yang, +13

Cell Biology and Toxicology

BiochemistryMedicineLipid PeroxidationDiabetesPharmacology +7

PI3K regulates the activation of NLRP3 inflammasome in atherosclerosis through part-dependent AKT signaling pathway

Zhenzhu Liu, Jing Li, Shu Lin, +3

EXPERIMENTAL ANIMALS

Kynurenic acid ameliorates NLRP3 inflammasome activation by blocking calcium mobilization via GPR35

Tianyin Sun, Ruiqian Xie, Hongbin He, +8

Frontiers in Immunology

Germacrone induces caspase‑3/GSDME activation and enhances ROS production, causing HepG2 pyroptosis

Xinfeng Sun, Wenfeng Ma, Wenxing Feng, +7

Experimental and Therapeutic Medicine

Acetylation is required for NLRP3 self-aggregation and full activation of the inflammasome

Kai Zhao, Yening Zhang, Xueming Xu, +6

ImmunologyMolecular BiologyPathologyNlrp3 Self-aggregationNlrp3 Full Activation +15

C646 Protects Against DSS-Induced Colitis Model by Targeting NLRP3 Inflammasome

Xueming Xu, Jing Li, Xiuyan Long, +5

Frontiers in Pharmacology

Chronic Inflammatory DiseasesNlrp3 Inflammasome AssemblyInflammatory Lung DiseaseLung InflammationImmunology +20

AZD8055 ameliorates experimental autoimmune encephalomyelitis via the mTOR/ROS/NLRP3 pathway

Miao He, Dongming Wu, Yangyang Zhao, +7

Biochemical and Biophysical Research Communications

Autoimmune DiseaseMedicineMtor/ros/nlrp3 PathwayImmunologyAutophagy +4