Bo Zhang

Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d

Bo Zhang, Yangmiao Ye, Weiwei Ye et al. · Nature Communications · 2019 · 110 citations · Full text

Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates

Xinyu Ling, Liying Chang, Heqi Chen et al. · Molecular Cell · 2021 · 61 citations · Full text

Engineering, Molecular Biology, Genetic Engineering +8

A Self‐Powered Wound Dressing Based on “Lock‐ON/OFF” Drug Release Combined Electric Stimulus Therapy for Accelerated Infected Wound Healing

Yani Sun, Yufei Tang, Yuxuan He et al. · Advanced Functional Materials · 2024 · 55 citations

Biomedical Sensors, Electrical Stimulation, Engineering +12

Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1

Bo Zhang, Diyin Luo, Yu Li et al. · Nature Communications · 2021 · 46 citations · Full text

Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system

Bo Zhang, Jinying Lin, Vanja Perčulija et al. · Nucleic Acids Research · 2022 · 28 citations · Full text

Off-target Effect, Type V-c Crispr-cas, Medicine +12