Jie Chen

MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways

Longlong Bao, Yan Yan, Can Xu et al. · Cancer Letters · 2013 · 181 citations

Hsulf-1 Expression, Hepatology, Microrna-21 Suppresses Pten +10

Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

Tessa Knox, Eva Sahakian, Debarati Banik et al. · Scientific Reports · 2019 · 158 citations · Full text

Improving stability of nitrile hydratase by bridging the salt-bridges in specific thermal-sensitive regions

Jie Chen, Huimin Yu, Changchun Liu et al. · Journal of Biotechnology · 2013 · 95 citations

Specific Thermal-sensitive Regions, Catalysis, Chemistry +2

The initial evaluation of non-peptidic small-molecule HDM2 inhibitors based on p53–HDM2 complex structure

Jianhua Zhao, Mijuan Wang, Jie Chen et al. · Cancer Letters · 2002 · 80 citations

Molecular Pharmacology, Initial Evaluation, Medicine +9

In Vitro Effect of Standardized Ginseng Extracts and Individual Ginsenosides on the Catalytic Activity of Human CYP1A1, CYP1A2, and CYP1B1

Thomas K. H. Chang, Jie Chen, Salete Benetton · Drug Metabolism and Disposition · 2002 · 75 citations