Altered angiotensin-converting enzyme and its effects on the brain in a rat model of Alzheimer disease

Deren Hou, Yan Wang, Lin Zhou, +5

Chinese Medical Journal

AgingNeurochemical BiomarkersRat ModelAlzheimer's DiseaseDegenerative Pathology +21

Hypoxia Induces M2 Macrophages to Express VSIG4 and Mediate Cardiac Fibrosis After Myocardial Infarction

Yan Wang, Yu Zhang, Jiao Li, +8

Theranostics

AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis

Bryna S.M. Chow, Martina Kočan, Matthew Shen, +17

Journal of the American Society of Nephrology

β-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats

Mark Del Borgo, Yan Wang, Sanja Bosnyak, +9

Clinical Science

HypertensionImmunologyCardiovascular PharmacologyRenal InflammationPeptide Science +22

The ACE2-Angiotensin-(1–7)-Mas Axis Protects Against Pancreatic Cell Damage in Cell Culture

Jing Wang, Ruixia Liu, Haiyu Qi, +5

Pancreas

Serelaxin and the AT₂ Receptor Agonist CGP42112 Evoked a Similar, Nonadditive, Cardiac Antifibrotic Effect in High Salt-Fed Mice That Were Refractory to Candesartan Cilexetil

Yan Wang, Lei Han, Matthew Shen, +7

ACS Pharmacology & Translational Science

B cell subsets contribute to myocardial protection by inducing neutrophil apoptosis after ischemia and reperfusion

Fang‐Yang Huang, Jialiang Zhang, Hao Zhou, +7

JCI Insight

Heart FailureApoptosisImmunologyCell DeathNeutrophil Apoptosis +19

MicroRNA-29b upregulation improves myocardial fibrosis and cardiac function in myocardial infarction rats through targeting SH2B3.

Yan Wang, B-J Jin, Qing Chen, +2

PubMed

Angiotensin‑(1‑7) prevents lipopolysaccharide‑induced hepatocellular inflammatory response by inhibiting the p38MAPK/AP‑1 signaling pathway

Hongli Xiao, Xiaoya Liu, Yan Wang, +2

Molecular Medicine Reports

P38 MitogenLiver FibrosisImmunologyImmune RegulationPathology +21

Novel AT2R agonist, β-Pro7Ang III, is cardio- and vaso-protective in diabetic spontaneously hypertensive rats

Mandy Li, Levi Nguyen, Dorota Ferens, +10

Biomedicine & Pharmacotherapy