Novel loci and pathways significantly associated with longevity

Yi Zeng, Chao Nie, Junxia Min, +54

Scientific Reports

PM2.5 induces autophagy and apoptosis through endoplasmic reticulum stress in human endothelial cells

Yán Wāng, Meng Tang

The Science of The Total Environment

InflammationCell AutophagyMitophagyApoptosisAutophagy +11

Functionalized MoS₂-Based Nanomaterials for Cancer Phototherapy and Other Biomedical Applications

Meng Liu, Houjuan Zhu, Yán Wāng, +2

ACS Materials Letters

NanoparticlesMolybdenum DisulfideNanotherapeuticsEngineeringNanosheet +18

GelMA-MXene hydrogel nerve conduits with microgrooves for spinal cord injury repair

Jiaying Cai, Hui Zhang, Yangnan Hu, +11

Journal of Nanobiotechnology

Tissue EngineeringGelma-mxene HydrogelEngineeringPeripheral Nerve InjuryBiofabrication +14

Multiple gene methylation of nonsmall cell lung cancers evaluated with 3‐dimensional microarray

Yán Wāng, Dingdong Zhang, Wenli Zheng, +3

Cancer

Activation of microglial P2Y12 receptor is required for outward potassium currents in response to neuronal injury

Przemyslaw Swiatkowski, Madhuvika Murugan, Ukpong B. Eyo, +4

Neuroscience

Outward Potassium CurrentsNeurophysiologyNeuronal InjuryMedicinePhysiology +12

Identification of mRNA-miRNA crosstalk in human endothelial cells after exposure of PM2.5 through integrative transcriptome analysis

Yán Wāng, Lingyue Zou, Tianshu Wu, +5

Ecotoxicology and Environmental Safety

InflammationMrna-mirna CrosstalkImmunologyEndothelial DysfunctionIntegrative Transcriptome Analysis +9

Ambient particulate matter triggers dysfunction of subcellular structures and endothelial cell apoptosis through disruption of redox equilibrium and calcium homeostasis

Yán Wāng, Tianshu Wu, Meng Tang

Journal of Hazardous Materials

Redox EquilibriumApoptosisCell DeathRedox BiologyCellular Physiology +14

Fluphenazine Reduces Proteotoxicity in C. elegans and Mammalian Models of Alpha-1-Antitrypsin Deficiency

Jie Li, Stephen C. Pak, Linda P. O’Reilly, +8

PLoS ONE

Cell DeathAlpha-1-antitrypsin DeficiencyToxicological MechanismOxidative StressSystems Pharmacology +20

A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnover

Olivia S. Long, Joshua A. Benson, Joon Hyeok Kwak, +13

Human Molecular Genetics

Protein TurnoverMolecular BiologyHuman α1-Antitrypsin DeficiencyTranscriptional RegulationSignaling Pathway +21