Le Fang

Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy

Hongtao Chen, Zhanyang Qian, Sheng Zhang et al. · Redox Biology · 2020 · 64 citations · Full text

Veterinary Medicine, Pathobiology, Pharmacology +17

Endogenous tryptophan metabolite 5-Methoxytryptophan inhibits pulmonary fibrosis by downregulating the TGF-β/SMAD3 and PI3K/AKT signaling pathway

Le Fang, Hongtao Chen, Renyi Kong et al. · Life Sciences · 2020 · 47 citations

Medicine, Cell Biology, Pharmacology +6

Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma

Xin Hong, Fan Jiang, You Li et al. · International Immunopharmacology · 2020 · 31 citations

Medicine, Neuroscience, Pharmacology +14

Punicalagin induces ROS‐mediated apoptotic cell death through inhibiting STAT3 translocation in lung cancer A549 cells

Le Fang, Hong Wang, Jie Zhang et al. · Journal of Biochemical and Molecular Toxicology · 2021 · 27 citations

Medicine, Oncology, Pharmacology +12

miR-766-3p Targeting BCL9L Suppressed Tumorigenesis, Epithelial-Mesenchymal Transition, and Metastasis Through the β-Catenin Signaling Pathway in Osteosarcoma Cells

Sheng Zhang, Hongtao Chen, Wanshun Liu et al. · Frontiers in Cell and Developmental Biology · 2020 · 25 citations · Full text

Medicine, Cancer Biology, Oncology +17