Jolien Van den Bossche

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer

Christophe Deben, An Wouters, Ken Op de Beeck et al. · Oncotarget · 2015 · 74 citations · Full text

Medicine, Oncology, Pharmacology +17

Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation

Julie Jacobs, Vanessa Deschoolmeester, Karen Zwaenepoel et al. · OncoImmunology · 2018 · 65 citations · Full text

Medicine, Immunology, Oncology +15

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress

Christophe Deben, Vanessa Deschoolmeester, Jorrit De Waele et al. · Cancers · 2018 · 64 citations · Full text

Medicine, Oncology, Pharmacology +17

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

Julie Jacobs, Karen Zwaenepoel, Christian Rolfo et al. · Oncotarget · 2015 · 62 citations · Full text

Medicine, Immunology, Oncology +16

APR-246 (PRIMA-1 MET ) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

Christophe Deben, Filip Lardon, An Wouters et al. · Cancer Letters · 2016 · 59 citations

Medicine, Oncology, Pharmacology +14