Gaku Tsuji

An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway

Gaku Tsuji, Masakazu Takahara, Hiroshi Uchi et al. · Journal of Dermatological Science · 2011 · 206 citations

Pharmacy, Dermatology, Toxicology +17

Identification of Ketoconazole as an AhR-Nrf2 Activator in Cultured Human Keratinocytes: The Basis of Its Anti-Inflammatory Effect

Gaku Tsuji, Masakazu Takahara, Hiroshi Uchi et al. · Journal of Investigative Dermatology · 2011 · 167 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis

Gaku Tsuji, Akiko Hashimoto‐Hachiya, Mari Kiyomatsu‐Oda et al. · Cell Death and Disease · 2017 · 142 citations · Full text

Life Sciences, Dermatology, Genetics +13

The <scp>IL</scp>‐13/periostin/<scp>IL</scp>‐24 pathway causes epidermal barrier dysfunction in allergic skin inflammation

Yasutaka Mitamura, Satoshi Nunomura, Yasuhiro Nanri et al. · Allergy · 2018 · 130 citations · Full text

Medicine, Dermatology, Immunology +17

Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis

Gaku Tsuji, Akiko Hashimoto‐Hachiya, Yen Hai Vu et al. · Cell Death Discovery · 2020 · 90 citations · Full text

Life Sciences, Dermatology, Immunology +17