Simone Grannò

Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity

Jonathon Nixon‐Abell, Daniel C. Berwick, Simone Grannò et al. · Frontiers in Molecular Neuroscience · 2016 · 71 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling

Daniel C. Berwick, Behzâd Javaheri, Andrea Wetzel et al. · Molecular Neurodegeneration · 2017 · 52 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus

Simone Grannò, Jonathon Nixon‐Abell, Daniel C. Berwick et al. · Scientific Reports · 2019 · 29 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Missense Mutation R338W in ARHGEF9 in a Family with X-linked Intellectual Disability with Variable Macrocephaly and Macro-Orchidism

Philip Long, Melanie May, Victoria M. James et al. · Frontiers in Molecular Neuroscience · 2016 · 26 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Dysregulated Wnt and NFAT signaling in a Parkinson’s disease LRRK2 G2019S knock-in model

Andrea Wetzel, Si Hang Lei, Tiansheng Liu et al. · Scientific Reports · 2024 · 19 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17