Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Daniel Taliun, Daniel Harris, Michael D. Kessler, +416

Nature

A structural variation reference for medical and population genetics

Ryan L. Collins, Harrison Brand, Konrad J. Karczewski, +27

Nature

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Alexander G. Bick, Joshua S. Weinstock, Satish K. Nandakumar, +405

Nature

Genetic DisorderGeneticsHematologyInherited CausesChromosomal Rearrangement +1

The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies

Claire Redin, Harrison Brand, Ryan L. Collins, +146

Nature Genetics

Human Congenital AnomaliesDevelopmental AnomalyDevelopmental BiologyCytogeneticsGenomic Landscape +6

Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome

Ryan L. Collins, Harrison Brand, Claire Redin, +27

Genome biology

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

Seung Hoan Choi, Lu‐Chen Weng, Carolina Roselli, +47

JAMA

Paired-Duplication Signatures Mark Cryptic Inversions and Other Complex Structural Variation

Harrison Brand, Ryan L. Collins, Carrie Hanscom, +12

The American Journal of Human Genetics

BioinformaticsSequence MotifGeneticsComputational BiologyCombinatorial Pattern Matching +5

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, +364

Nature Communications

Transmission of Single and Multiple Viral Variants in Primary HIV-1 Subtype C Infection

Vladimir Novitsky, Rui Wang, Lauren Margolin, +5

PLoS ONE

Evolution of proviral gp120 over the first year of HIV-1 subtype C infection

Vladimir Novitsky, Stephen W. Lagakos, Michaela Herzig, +11

Virology

First YearViral EvolutionMedicineHuman RetrovirusPathogenesis +6