Evolution and transmission of stable CTL escape mutations in HIV infection

Philip Goulder, Christian Brander, Yanhua Tang, +16

Nature

Viral EvolutionHuman RetrovirusPathogenesisImmunologyHiv Infection +8

Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

Florencia Pereyra, Marylyn M. Addo, Daniel E. Kaufmann, +14

The Journal of Infectious Diseases

Association between Virus-Specific Cytotoxic T-Lymphocyte and Helper Responses in Human Immunodeficiency Virus Type 1 Infection

Spyros A. Kalams, Susan Buchbinder, Eric Rosenberg, +6

Journal of Virology

Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms

Otto O. Yang, Spyros A. Kalams, Alicja Trocha, +4

Journal of Virology

Hla ImmunogeneticsImmunologyImmunotherapyHuman RetrovirusCd8+ Cells +16

Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection. Breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load

Thomas Harrer, Ellen G. Harrer, Spyros A. Kalams, +7

The Journal of Immunology

Levels of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T-Lymphocyte Effector and Memory Responses Decline after Suppression of Viremia with Highly Active Antiretroviral Therapy

Spyros A. Kalams, Philip Goulder, Amy Shea, +4

Journal of Virology

HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition

Toshiyuki Miura, Mark A. Brockman, Arne Schneidewind, +17

Journal of Virology

HistocompatibilityElite ControllersHla ImmunogeneticsImmunologyTw10 Epitope +14

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.

Spyros A. Kalams, R. Paul Johnson, Alicja Trocha, +5

The Journal of Experimental Medicine

Longitudinal AnalysisAdaptive Immune SystemImmunologyImmunodominanceCd4 T Cell Responses +18

Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes

Otto O. Yang, Spyros A. Kalams, Michael Rosenzweig, +5

Journal of Virology

Primary ImmunodeficiencyCytotoxic T LymphocytesCd4+ Cell LinesEfficient LysisHuman Retrovirus +13

Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes

R. Brad Jones, Rachel W O’Connor, Stefanie Mueller, +9

PLoS Pathogens

Cytotoxic T-lymphocytesCandidate HdaciAdaptive Immune SystemImmunologyImmune Regulation +22