Anastasia C. Murthy

Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain

Anastasia C. Murthy, Gregory L. Dignon, Yelena Kan et al. · Nature Structural & Molecular Biology · 2019 · 801 citations · Full text

Natural Sciences, Chemistry, Physics +16

SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs

Theodora Myrto Perdikari, Anastasia C. Murthy, Veronica H. Ryan et al. · The EMBO Journal · 2020 · 355 citations · Full text

Life Sciences, Biology, Molecular Biology +17

Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads

Anastasia C. Murthy, Wai Shing Tang, Nina Jovic et al. · Nature Structural & Molecular Biology · 2021 · 157 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models

Hiroyuki Uechi, Sindhuja Sridharan, Jik Nijssen et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 91 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

N‐terminal acetylation modestly enhances phase separation and reduces aggregation of the low‐complexity domain of RNA‐binding protein fused in sarcoma

Anna S. Bock, Anastasia C. Murthy, Wai Shing Tang et al. · Protein Science · 2021 · 57 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17