Jon R. Heylings

A multi-laboratory evaluation of a common in vitro pepsin digestion assay protocol used in assessing the safety of novel proteins

Karluss Thomas, M. Aalbers, Gary A. Bannon et al. · Regulatory Toxicology and Pharmacology · 2004 · 284 citations

Life Sciences, Biochemistry, Food Science +16

Multi-species assessment of electrical resistance as a skin integrity marker for in vitro percutaneous absorption studies

Diane J. Davies, Roberta J. Ward, Jon R. Heylings · Toxicology in Vitro · 2004 · 234 citations

Nursing, Biomedical Engineering, Pharmacokinetics +15

The ECVAM International Validation Study on in Vitro Tests for Acute Skin Irritation: Report on the Validity of the EPISKIN and EpiDerm Assays and on the Skin Integrity Function Test

Horst Spielmann, Sebastian Hoffmann, Manfred Liebsch et al. · Alternatives to Laboratory Animals · 2007 · 223 citations

Pharmacy, Dermatology, Toxicology +11

Surface epithelial HCO3(-) transport by mammalian duodenum in vivo

Gunnar Flemström, A. Garner, Olof Nylander et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 1982 · 168 citations

Engineering, Veterinary Physiology, Biological Transport Phenomena +12

Methods for Assessing Percutaneous Absorption

Doug Howes, Richard H. Guy, Jonathan Hadgraft et al. · Alternatives to Laboratory Animals · 1996 · 155 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +11