Angus N. M. Weir

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

Mitja M. Zdouc, Kai Blin, Nico L L Louwen et al. · Nucleic Acids Research · 2024 · 206 citations · Full text

Life Sciences, Bioinformatics, Biotechnology +17

The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in <i>Staphylococcus aureus</i> by Targeting the Enoyl‐Acyl Carrier Protein Binding Site of FabI

Christopher D. Fage, Thomas Lathouwers, Michiel Vanmeert et al. · Angewandte Chemie International Edition · 2020 · 29 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Control of β‐Branching in Kalimantacin Biosynthesis: Application of ¹³C NMR to Polyketide Programming

Paul D. Walker, Christopher Williams, Angus N. M. Weir et al. · Angewandte Chemie International Edition · 2019 · 21 citations

Pharmacy, Molecular Biology, Enzyme Mechanism +16

Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin

Ashley J. Winter, Matthew Rowe, Angus N. M. Weir et al. · Angewandte Chemie International Edition · 2022 · 14 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis

Paul D. Walker, Matthew Rowe, Ashley J. Winter et al. · ACS Chemical Biology · 2020 · 11 citations · Full text

Life Sciences, Biochemistry, Microbiology +17