Cheng Shen

Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling

Shouya Feng, Daniel Enosi Tuipulotu, Abhimanu Pandey et al. · Nature Communications · 2022 · 48 citations · Full text

Microbial Pathogens, Innate Immune System, Immunology +21

Inflammasomes in Colitis and Colorectal Cancer: Mechanism of Action and Therapies.

Abhimanu Pandey, Cheng Shen, Si Ming Man · PubMed · 2019 · 36 citations

Chronic Inflammatory Diseases, Dysbiosis, Immunology +21

<i>Clostridium septicum</i> α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins

Weidong Jing, Jordan Lo Pilato, Callum Kay et al. · Science Immunology · 2022 · 36 citations

Immunity against <i>Moraxella catarrhalis</i> requires guanylate‐binding proteins and caspase‐11‐ <scp>NLRP3</scp> inflammasomes

Daniel Enosi Tuipulotu, Shouya Feng, Abhimanu Pandey et al. · The EMBO Journal · 2023 · 35 citations · Full text

Microbe-Derived Antioxidants Reduce Lipopolysaccharide-Induced Inflammatory Responses by Activating the Nrf2 Pathway to Inhibit the ROS/NLRP3/IL-1β Signaling Pathway

Cheng Shen, Zhen Luo, Sheng Ma et al. · International Journal of Molecular Sciences · 2022 · 21 citations · Full text

Microbe-derived Antioxidants, Inflammatory Lung Disease, Lung Inflammation +23