Zabdi González‐Chávez

Drug target validation of the trypanothione pathway enzymes through metabolic modelling

Viridiana Olín‐Sandoval, Zabdi González‐Chávez, Miriam Berzunza‐Cruz et al. · FEBS Journal · 2012 · 52 citations

Metabolic control analysis of the Trypanosoma cruzi peroxide detoxification pathway identifies tryparedoxin as a suitable drug target

Zabdi González‐Chávez, Viridiana Olín‐Sandoval, José S. Rodríguez‐Zavala et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2014 · 34 citations

Biochemistry, Metabolic Control Analysis, Medicine +9

Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity

Zabdi González‐Chávez, Citlali Vázquez, Marlen Mejia‐Tlachi et al. · Redox Biology · 2019 · 31 citations · Full text

Buthionine sulfoximine is a multitarget inhibitor of trypanothione synthesis in <i>Trypanosoma cruzi</i>

Citlali Vázquez, Marlen Mejia‐Tlachi, Zabdi González‐Chávez et al. · FEBS Letters · 2017 · 18 citations · Full text

Synthesis and biological evaluation of 2-methyl-1H-benzimidazole-5-carbohydrazides derivatives as modifiers of redox homeostasis of Trypanosoma cruzi

Silvia Melchor-Doncel de la Torre, Citlali Vázquez, Zabdi González‐Chávez et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 15 citations

Trypanosoma Cruzi, Biochemistry, Parasitic Protozoa +6