Akira Mizusuna

Rational Drug Design and Synthesis of a Highly Selective Nonpeptide .DELTA.-Opioid Agonist, (4aS*,12aR*)-4a-(3-Hydroxyphenyl)-2-methyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridine (TAN-67).

Hiroshi Nagase, Koji Kawai, Jun Hayakawa et al. · Chemical and Pharmaceutical Bulletin · 1998 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Delta-1 Opioid Receptor-Mediated Antinociceptive Properties of a Nonpeptidic Delta Opioid Receptor Agonist, (−)TAN-67, in the Mouse Spinal Cord

L F Tseng, Minoru Narita, H Mizoguchi et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 49 citations

Medicine, Neuroscience, Pharmacology +17

Supraspinal δ1-opioid receptor-mediated antinociceptive properties of (−)-TAN-67 in diabetic mice

Junzo Kamei, K Kawai, Akira Mizusuna et al. · European Journal of Pharmacology · 1997 · 34 citations

Medicine, Neuroscience, Pharmacology +13

Novel cyclo-oligomerization of nickel carbenoids: a simple and efficient synthesis of radialenes

Iyoda Masahiko, Akira Mizusuna, Hiroyuki Kurata et al. · Journal of the Chemical Society Chemical Communications · 1989 · 22 citations

Natural Sciences, Chemistry, Organic Chemistry +7

Synthesis of optically active TAN-67, a highly selective delta opioid receptor agonist, and investigation of its pharmacological properties.

H. Fujii, Koji Kawai, Kuniaki Kawamura et al. · PubMed · 2001 · 18 citations

Medicine, Medicinal Chemistry, Pharmacology +15