Wayne Pearce

Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice

Klaus Okkenhaug, Antonio Bilancio, Géraldine Farjot et al. · Science · 2002 · 929 citations

Immunology, Cell Death, Immunologic Mechanism +17

Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

Khaled Ali, Dalya R. Soond, Roberto Piñeiro et al. · Nature · 2014 · 529 citations · Full text

Cancer Immunosurveillance, T-regulatory Cell, Immunology +9

Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration

Mariona Graupera, Julie Guillermet‐Guibert, Lazaros C. Foukas et al. · Nature · 2008 · 510 citations

Developmental Biology, Angiogenesis, Signaling Pathway +8

Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation

Lazaros C. Foukas, Marc Claret, Wayne Pearce et al. · Nature · 2006 · 456 citations

Signal Transduction, Signaling Pathway, Critical Role +12

Essential role for the p110δ phosphoinositide 3-kinase in the allergic response

Khaled Ali, Antonio Bilancio, Matthew J. Thomas et al. · Nature · 2004 · 377 citations · Full text

Asthma, P110δ Phosphoinositide 3-Kinase, Molecular Physiology +10