R E Clark

Expression of the Uptake Drug Transporter hOCT1 is an Important Clinical Determinant of the Response to Imatinib in Chronic Myeloid Leukemia

L Wang, Athina Giannoudis, Steven Lane et al. · Clinical Pharmacology & Therapeutics · 2007 · 277 citations

Medicine, Oncology, Pharmacotherapy +13

Chronic myeloid leukemia patients with the e13a2 BCR-ABL fusion transcript have inferior responses to imatinib compared to patients with the e14a2 transcript

Claire Lucas, Robert J. Harris, Athina Giannoudis et al. · Haematologica · 2009 · 118 citations · Full text

Life Sciences, Hematology, Oncology +14

Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter

R E Clark, Ian D. Kerr, Richard Callaghan · British Journal of Pharmacology · 2006 · 107 citations · Full text

Medicine, Oncology, Pharmacology +17

Nilotinib concentration in cell lines and primary CD34+ chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters

Andrea Davies, Niove E. Jordanides, Athina Giannoudis et al. · Leukemia · 2009 · 102 citations

Medicine, Oncology, Pharmacology +15

Previous treatment predicts the efficiency of blood progenitor cell mobilisation: validation of a chemotherapy scoring system

R E Clark, C. Brammer · Bone Marrow Transplantation · 1998 · 66 citations

Medicine, Hematology, Oncology +9