Concepedia

Sigal Saphier

SS

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Publications

17

Citations

1.4K

H-Index

13

Active since

1997

Affiliations

Israel Institute for Biological Research(Current)

Technion – Israel Institute of Technology

Scripps Research Institute

Hebrew University of Jerusalem

Sigal Saphier is an author at Israel Institute for Biological Research specializing in chemistry, medicinal chemistry, and natural sciences.

ORCID

Publications per year

1997–2024

17

Publications

17

Difluoromethyl Bioisostere: Examining the “Lipophilic Hydrogen Bond Donor” Concept

Yossi Zafrani, Dina Yeffet, Gali Sod‐Moriah et al. · Journal of Medicinal Chemistry · 2017 · 638 citations

, , +14

CF <sub>2</sub> H, a Functional Group-Dependent Hydrogen-Bond Donor: Is It a More or Less Lipophilic Bioisostere of OH, SH, and CH <sub>3</sub> ?

Yossi Zafrani, Gali Sod‐Moriah, Dina Yeffet et al. · Journal of Medicinal Chemistry · 2019 · 336 citations

, , +14

An Efficient Sol−Gel Reactor for Antibody-Catalyzed Transformations

Doron Shabat, Flavio Grynszpan, Sigal Saphier et al. · Chemistry of Materials · 1997 · 66 citations

, , +17

Modulation of the H-Bond Basicity of Functional Groups by α-Fluorine-Containing Functions and its Implications for Lipophilicity and Bioisosterism

Yossi Zafrani, Galit Parvari, Dafna Amir et al. · Journal of Medicinal Chemistry · 2021 · 59 citations

, , +17

Gastro intestinal tracking and gastric emptying of solid dosage forms in rats using X-ray imagining

Sigal Saphier, Amir Rosner, Rachel Brandeis et al. · International Journal of Pharmaceutics · 2010 · 58 citations

, , +15

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