Arwel Lewis

A Model for Nonstoichiometric, Cotranslational Protein Scission in Eukaryotic Ribosomes

Martin D. Ryan, Michelle Donnelly, Arwel Lewis et al. · Bioorganic Chemistry · 1999 · 71 citations

Prokaryotic System, Protein Assembly, Protein Folding +9

Synthesis of fused 1,2,5-triazepine-1,5-diones and some N2- and N3-substituted derivatives: potential conformational mimetics for cis-peptidyl prolinamides 1

Morag M. Lenman, Arwel Lewis, David Gani · Journal of the Chemical Society Perkin Transactions 1 · 1997 · 36 citations

Synthesis of (2S,3S)-β-methyltryptophan

Guoxia Han, Arwel Lewis, Victor J. Hruby · Tetrahedron Letters · 2001 · 24 citations

Organic Chemistry, Synthesis Method, Chemistry +2

Design, construction and properties of peptide N-terminal cap templates devised to initiate α-helices. Part 2.† Caps derived from N-[(2S )-2-chloropropionyl]-(2S )-Pro-(2S )-Pro-(2S,4S )-4-thioPro-OMe

Arwel Lewis, John Wilkie, Trevor J. Rutherford et al. · Journal of the Chemical Society Perkin Transactions 1 · 1998 · 21 citations

Biochemistry, Natural Sciences, Peptide Engineering +15

Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors

David Harrison, Mark G. Bock, John R. Doedens et al. · ACS Medicinal Chemistry Letters · 2022 · 20 citations · Full text