Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

Yuyu Niu, Bin Shen, Yiqiang Cui, +25

Cell

Gene TherapiesDevelopmental BiologyNatural SciencesCas9/rna-mediated Gene TargetingGenetic Engineering +10

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9

Yongchang Chen, Yinghui Zheng, Yu Kang, +12

Human Molecular Genetics

Dystrophin GeneEngineeringGeneticsMolecular GeneticsEarly Dmd +14

TALEN-Mediated Gene Mutagenesis in Rhesus and Cynomolgus Monkeys

Hailiang Liu, Yongchang Chen, Yuyu Niu, +29

Cell stem cell

BiologyGeneticsGenetic EngineeringGenetic MechanismMolecular Genetics +4

Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys

Yongchang Chen, Juehua Yu, Yuyu Niu, +34

Cell

Knockout MouseMendelian DisorderGenetic DisorderGeneticsMolecular Genetics +2

Dissecting primate early post-implantation development using long-term in vitro embryo culture

Yuyu Niu, Nianqin Sun, Chang Li, +21

Science

FertilityGeneticsBiomedical EngineeringReproductive BiologyPrimate Systematics +21

Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo

Tao Tan, Jun Wu, Chenyang Si, +23

Cell

Regenerative MedicineEmbryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyPluripotent Stem Cells +12

Generation of Cynomolgus Monkey Chimeric Fetuses using Embryonic Stem Cells

Yongchang Chen, Yuyu Niu, Yanjiao Li, +12

Cell stem cell

BiologyEmbryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyMedicine +7

Amnion signals are essential for mesoderm formation in primates

Ran Yang, Alexander Goedel, Yu Kang, +16

Nature Communications

Generation of a Hutchinson–Gilford progeria syndrome monkey model by base editing

Fang Wang, Weiqi Zhang, Qiaoyan Yang, +15

Protein & Cell

De novo DNA methylation during monkey pre-implantation embryogenesis

Fei Gao, Yuyu Niu, Yi Eve Sun, +13

Cell Research