Sarah C. Zimmermann

Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer

Amira Elgogary, Qingguo Xu, Brad Poore et al. · Proceedings of the National Academy of Sciences · 2016 · 231 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

<i>N</i>-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-<scp>l</scp>-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders

Michael T. Nedelcovych, Lukáš Tenora, Boe-Hyun Kim et al. · Journal of Medicinal Chemistry · 2017 · 68 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation

Camilo Rojas, Elena Barnaeva, Ajit G. Thomas et al. · Scientific Reports · 2018 · 67 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Allosteric Glutaminase Inhibitors Based on a 1,4-Di(5-amino-1,3,4-thiadiazol-2-yl)butane Scaffold

Sarah C. Zimmermann, Emily F. Wolf, Andrew Luu et al. · ACS Medicinal Chemistry Letters · 2016 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Structural basis for exploring the allosteric inhibition of human kidney type glutaminase

Sarath Ramachandran, Catherine Pan, Sarah C. Zimmermann et al. · Oncotarget · 2016 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14