James N. Riggins

Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein

Lawrence J. Marnett, James N. Riggins, James D. West · Journal of Clinical Investigation · 2003 · 397 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Covalent Adduction of Human Serum Albumin by 4-Hydroxy-2-Nonenal: Kinetic Analysis of Competing Alkylation Reactions

Matthew Szapacs, James N. Riggins, Lisa J. Zimmerman et al. · Biochemistry · 2006 · 82 citations

Pharmacy, Biochemistry, Toxicology +17

Reactivity and Mutagenicity of Endogenous DNA Oxopropenylating Agents:  Base Propenals, Malondialdehyde, and <i>N</i>^ε-Oxopropenyllysine

John P. Plastaras, James N. Riggins, Michael B. Otteneder et al. · Chemical Research in Toxicology · 2000 · 75 citations

Pharmacy, Molecular Biology, Toxicology +16

Malondialdehyde adducts in DNA arrest transcription by T7 RNA polymerase and mammalian RNA polymerase II

Susan D. Cline, James N. Riggins, Silvia Tornaletti et al. · Proceedings of the National Academy of Sciences · 2004 · 72 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Kinetics and Mechanism of the General-Acid-Catalyzed Ring-Closure of the Malondialdehyde−DNA Adduct, <i>N</i>²-(3-Oxo-1-propenyl)deoxyguanosine (<i>N</i><i>²</i>OPdG^-), to 3-(2‘-Deoxy-β-<scp>d</scp>-<i>erythro</i>-pentofuranosyl)pyrimido[1,2-α]purin- 10(3<i>H</i>)-one (M₁dG)

James N. Riggins, Derek A. Pratt, Markus Voehler et al. · Journal of the American Chemical Society · 2004 · 57 citations

Life Sciences, Biochemistry, Molecular Biology +13