Michael C. Young

Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes

Yi Sun, Michael C. Young, Claire H. Woodward et al. · Proceedings of the National Academy of Sciences · 2023 · 29 citations · Full text

Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes

Yi Sun, Georgia Papadaki, Christine A. Devlin et al. · Science Advances · 2023 · 20 citations · Full text

Histocompatibility, Hla, Hla Immunogenetics +21

Targeting peptide antigens using a multiallelic MHC I-binding system

Haotian Du, Leena Mallik, Daniel Hwang et al. · Nature Biotechnology · 2024 · 20 citations · Full text

Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion

Yi Sun, Tyler J. Florio, S. K. Gupta et al. · Science Immunology · 2023 · 17 citations · Full text

Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules

Georgia Papadaki, Omar Ani, Tyler J. Florio et al. · Frontiers in Immunology · 2023 · 11 citations · Full text