A. M. Oficialdegui

New 1-Aryl-3-(4-arylpiperazin-1-yl)propane Derivatives, with Dual Action at 5-HT_1ASerotonin Receptors and Serotonin Transporter, as a New Class of Antidepressants

Javier Martínez-Esparza, A. M. Oficialdegui, Silvia Pérez‐Silanes et al. · Journal of Medicinal Chemistry · 2000 · 73 citations · Full text

Synthesis and Molecular Modeling of New 1-Aryl-3-[4-arylpiperazin-1-yl]-1-propane Derivatives with High Affinity at the Serotonin Transporter and at 5-HT_1A Receptors

L. Orus, Silvia Pérez‐Silanes, A. M. Oficialdegui et al. · Journal of Medicinal Chemistry · 2002 · 45 citations · Full text

Design, synthesis and biological evaluation of new 3-[(4-aryl)piperazin-1-yl]-1-arylpropane derivatives as potential antidepressants with a dual mode of action: serotonin reuptake inhibition and 5-HT1A receptor antagonism

A. M. Oficialdegui, Jean Martínez, Begoña Heras et al. · Il Farmaco · 2000 · 39 citations

Serotonin Reuptake Inhibition, Medicinal Chemistry, Functional Selectivity +9

Synthesis of new 5‐substitutedbenzo[<i>b</i>]thiophene derivatives

Silvia Pérez‐Silanes, Javier Martínez-Esparza, A. M. Oficialdegui et al. · Journal of Heterocyclic Chemistry · 2001 · 33 citations

Serotonin Reuptake Inhibition, Medicinal Chemistry, Derivative (Chemistry) +12