William J Jowsey

An epigenetic switch activates bacterial quorum sensing and horizontal transfer of an integrative and conjugative element

Joshua P. Ramsay, Tahlia R. Bastholm, Callum Verdonk et al. · Nucleic Acids Research · 2021 · 33 citations · Full text

Life Sciences, Genetics, Microbiology +13

Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium tuberculosis

William J Jowsey, Chen‐Yi Cheung, C. Smart et al. · Nature Communications · 2024 · 22 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis

Cara Adolph, Chen‐Yi Cheung, Matthew B. McNeil et al. · Cell chemical biology · 2023 · 19 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Verapamil and its metabolite norverapamil inhibit the <i>Mycobacterium tuberculosis</i> MmpS5L5 efflux pump to increase bedaquiline activity

Adam J. Fountain, Natalie J.E. Waller, Chen‐Yi Cheung et al. · Proceedings of the National Academy of Sciences · 2025 · 17 citations · Full text

Life Sciences, Pharmacology, Pharmacotherapy +16

Structure and assembly of the MmpL5/MmpS5 efflux transporter from Mycobacterium tuberculosis

Zhi‐Qi Xiong, Xiaolin Yang, Shule Wang et al. · Nature Communications · 2025 · 10 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17