Wen‐Tsan Chang

Endoplasmic Reticulum Stress Stimulates the Expression of Cyclooxygenase-2 through Activation of NF-κB and pp38 Mitogen-activated Protein Kinase

Jui‐Hsiang Hung, Ih‐Jen Su, Huan-Yao Lei et al. · Journal of Biological Chemistry · 2004 · 257 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy

Chin-Chih Lin, Tsung‐Lin Cheng, Wen-Hui Tsai et al. · Scientific Reports · 2012 · 182 citations · Full text

Medicine, Cancer Biology, Oncology +17

Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway

Chia‐Ling Chen, Chiou‐Feng Lin, Wen‐Tsan Chang et al. · Blood · 2008 · 181 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

A Marine Terpenoid, Heteronemin, Induces Both the Apoptosis and Ferroptosis of Hepatocellular Carcinoma Cells and Involves the ROS and MAPK Pathways

Wen‐Tsan Chang, Yung‐Ding Bow, Pei-Jung Fu et al. · Oxidative Medicine and Cellular Longevity · 2021 · 132 citations · Full text

Medicine, Oncology, Pharmacology +17

Sequential Caspase-2 and Caspase-8 Activation Upstream of Mitochondria during Ceramideand Etoposide-induced Apoptosis

Chiou‐Feng Lin, Chia Ling Chen, Wen‐Tsan Chang et al. · Journal of Biological Chemistry · 2004 · 127 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16