Thomas L. Joseph

Stapled Peptides with Improved Potency and Specificity That Activate p53

Christopher J. Brown, Soo Tng Quah, J.G.Y. de Jong et al. · ACS Chemical Biology · 2012 · 215 citations

Pharmacy, Medicinal Chemistry, Oncology +15

Functionalised staple linkages for modulating the cellular activity of stapled peptides

Yu Heng Lau, Peterson de Andrade, S.T. Quah et al. · Chemical Science · 2014 · 214 citations

Life Sciences, Biochemistry, Molecular Biology +9

Molecular Rotors As Conditionally Fluorescent Labels for Rapid Detection of Biomolecular Interactions

Walter L. Goh, Min Yen Lee, Thomas L. Joseph et al. · Journal of the American Chemical Society · 2014 · 115 citations

Medicine, Medicinal Chemistry, Molecular Biology +17

Differential binding of p53 and nutlin to MDM2 and MDMX: Computational studies

Thomas L. Joseph, Arumugam Madhumalar, Christopher J. Brown et al. · Cell Cycle · 2010 · 87 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Stapled peptides in the p53 pathway: Computer simulations reveal novel interactions of the staples with the target protein

Thomas L. Joseph, David P. Lane, Chandra Verma · Cell Cycle · 2010 · 51 citations · Full text

Pharmacy, Chemical Biology, Molecular Biology +14