RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure

Zhipeng Lu, Qiangfeng Cliff Zhang, Byron Lee, +10

Cell

ChromatinFunctional GenomicsRna Duplex MapGeneticsRna Structure Prediction +7

Metazoan tRNA introns generate stable circular RNAs in vivo

Zhipeng Lu, Grigory S. Filonov, John J. Noto, +5

RNA

Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors

Wei Zhang, Si-Lu Yang, Mei Yang, +14

Nature Communications

Clinically applicable deep learning framework for organs at risk delineation in CT images

Hao Tang, Xuming Chen, Yang Liu, +9

Nature Machine Intelligence

Medical Image SegmentationImage AnalysisEngineeringMedical ImagingDeep Learning +11

A deep learning-based auto-segmentation system for organs-at-risk on whole-body computed tomography images for radiation therapy

Xuming Chen, Shanlin Sun, Narisu Bai, +12

Radiotherapy and Oncology

Cerebral organoid and mouse models reveal a RAB39b–PI3K–mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes

Wei Zhang, Li Ma, Mei Yang, +7

Genes & Development

RISE: a database of RNA interactome from sequencing experiments

Jing Gong, Kui Xu, Zhipeng Lu, +3

Nucleic Acids Research

EngineeringGeneticsTranscriptomics TechnologyRna InteractomeLong Non-coding Rna +15

Structural modularity of the XIST ribonucleoprotein complex

Zhipeng Lu, Jimmy K. Guo, Yuning Wei, +9

Nature Communications

Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential

Meng Jiang, Jiachen Fei, Michael S. Lan, +5

Diabetologia

Metabolic SyndromeInsulin SignalingDevelopmental BiologyLiver PhysiologyDiabetes +10

REV3L confers chemoresistance to cisplatin in human gliomas: The potential of its RNAi for synergistic therapy

Huibo Wang, Shuyu Zhang, Shuai Wang, +12

Neuro-Oncology

High-grade GliomasSynergistic TherapyCancer BiologyGliomaTumor Biology +15