Eric C. Freeman

Modeling the proton sponge hypothesis: examining proton sponge effectiveness for enhancing intracellular gene delivery through multiscale modeling

Eric C. Freeman, Lisa Mauck Weiland, Wilson S. Meng · Journal of Biomaterials Science Polymer Edition · 2012 · 143 citations · Full text

Biophysical Modeling, Sponge Protonation Model, Molecular Biology +20

Evaluating the therapeutic potential of ADAR1 inhibition for triple-negative breast cancer

Che-Pei Kung, Kyle A. Cottrell, Sua Ryu et al. · Oncogene · 2020 · 99 citations · Full text

Therapeutic Potential, Breast Oncology, Oncology +10

Electrophysiological interrogation of asymmetric droplet interface bilayers reveals surface-bound alamethicin induces lipid flip-flop

Graham J. Taylor, Mary-Anne Nguyen, Subhadeep Koner et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2018 · 50 citations · Full text

Surface-bound Alamethicin Induces, Proteinlipid Interaction, Engineering +8

Activation of bacterial channel MscL in mechanically stimulated droplet interface bilayers

Joseph S. Najem, Myles D. Dunlap, Ian Rowe et al. · Scientific Reports · 2015 · 46 citations · Full text

The mechanoelectrical response of droplet interface bilayer membranes

Eric C. Freeman, Joseph S. Najem, Sergei Sukharev et al. · Soft Matter · 2016 · 39 citations