Leonardo Santos

Engineered tRNAs suppress nonsense mutations in cells and in vivo

Suki Albers, Elizabeth Cheresh Allen, Nikhil Bharti et al. · Nature · 2023 · 117 citations · Full text

tRNA overexpression rescues peripheral neuropathy caused by mutations in tRNA synthetase

Amila Zuko, Moushami Mallik, Robin Thompson et al. · Science · 2021 · 116 citations · Full text

Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity

Robert Rauscher, Giovana Bampi, Marta Guevara‐Ferrer et al. · Proceedings of the National Academy of Sciences · 2021 · 39 citations · Full text

Positive Epistasis, Mendelian Disorder, Amino Acid +15

N6-methyladenosine in 5′ UTR does not promote translation initiation

Ewelina Guca, Rodrigo Alarcon, Michael Z. Palo et al. · Molecular Cell · 2024 · 36 citations · Full text

mRNAs sequestered in stress granules recover nearly completely for translation

Sarada Das, Leonardo Santos, Antonio Virgilio Failla et al. · RNA Biology · 2022 · 24 citations · Full text