Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma

Nayoung Kim, Hong Kwan Kim, Kyungjong Lee, +18

Nature Communications

Metastatic Lung AdenocarcinomaImmunologyCancer BiologyTumor BiologyTumor Heterogeneity +18

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Woosung Chung, Hye Hyeon Eum, Hae‐Ock Lee, +10

Nature Communications

Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer

Hae‐Ock Lee, Yourae Hong, Hakki Emre Etlioglu, +34

Nature Genetics

MedicineImmunologyImmune LandscapeColorectal CancerCancer Genomics +8

Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells

Kyu‐Tae Kim, Hye Won Lee, Hae‐Ock Lee, +8

Genome Biology

Spatiotemporal genomic architecture informs precision oncology in glioblastoma

Jin‐Ku Lee, Jiguang Wang, K. Jason, +26

Nature Genetics

Neuro-oncologyEngineeringTumor HeterogeneityMedicineCancer Genomics +5

Linking transcriptional and genetic tumor heterogeneity through allele analysis of single-cell RNA-seq data

Jean Fan, Hae‐Ock Lee, Soohyun Lee, +8

Genome Research

EngineeringGeneticsSingle-cell Rna-seq DataTranscriptomics TechnologyGenetic Tumor Heterogeneity +20

Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma

Kyu‐Tae Kim, Hye Won Lee, Hae‐Ock Lee, +10

Genome biology

Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient

Hye Won Lee, Woosung Chung, Hae‐Ock Lee, +9

Genome Medicine

SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells

Kyung Yeon Han, Kyu‐Tae Kim, Je‐Gun Joung, +15

Genome Research

Parallel SequencingGeneticsMolecular BiologyTotal RnaMultiomics +22

TRAIL: A Mechanism of Tumor Surveillance in an Immune Privileged Site

Hae‐Ock Lee, John M. Herndon, Ramon Barreiro, +2

The Journal of Immunology