Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner

Eiji Kakazu, Amy S. Mauer, Meng Yin, +1

Journal of Lipid Research

IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis

Debanjali Dasgupta, Yasuhiko Nakao, Amy S. Mauer, +20

Gastroenterology

InflammationMolecular PhysiologyHepatologyLiver PhysiologyImmunology +11

Hepatocyte-Derived Lipotoxic Extracellular Vesicle Sphingosine 1-Phosphate Induces Macrophage Chemotaxis

Chieh-Yu Liao, Myeong Jun Song, Yandong Gao, +3

Frontiers in Immunology

Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis

Amy S. Mauer, Petra Hirsova, Jessica L. Maiers, +2

American Journal of Physiology-Gastrointestinal and Liver Physiology

C/EBP Homologous Protein-induced Macrophage Apoptosis Protects Mice from Steatohepatitis

Harmeet Malhi, Erin M. Kropp, Vinna F. Clavo, +5

Journal of Biological Chemistry

Circulating Extracellular Vesicles Carrying Sphingolipid Cargo for the Diagnosis and Dynamic Risk Profiling of Alcoholic Hepatitis

Tejasav S. Sehrawat, Juan Pablo Arab, Mengfei Liu, +24

Hepatology

Calmodulin-like Protein Increases Filopodia-dependent Cell Motility via Up-regulation of Myosin-10

Richard D. Bennett, Amy S. Mauer, Emanuel E. Strehler

Journal of Biological Chemistry

ImmunologyCytoskeletonCell DifferentiationCellular PhysiologyTumor Biology +19

Characterization of Cellular Sources and Circulating Levels of Extracellular Vesicles in a Dietary Murine Model of Nonalcoholic Steatohepatitis

Jiahui Li, Huimin Liu, Amy S. Mauer, +8

Hepatology Communications

Circulating extracellular vesicles are a biomarker for NAFLD resolution and response to weight loss surgery

Yasuhiko Nakao, Pouya Amrollahi, Gopanandan Parthasarathy, +8

Nanomedicine Nanotechnology Biology and Medicine

InflammationExtracellular VesiclesMetabolic SyndromeBiomarker (Medicine)Loss Surgery +11

Prediction of nonalcoholic fatty liver disease (NAFLD) activity score (NAS) with multiparametric hepatic magnetic resonance imaging and elastography

Ziying Yin, Matthew C. Murphy, Jiahui Li, +9

European Radiology

Metabolic SyndromeBody CompositionHepatologyMetabolic Associated Steatotic Liver DiseaseMedical Imaging +9