W. Ewan Hume

Oxindole Derivatives as Orally Active Potent Growth Hormone Secretagogues

Teruhisa Tokunaga, W. Ewan Hume, Takashi Umezome et al. · Journal of Medicinal Chemistry · 2001 · 286 citations

Medicinal Chemistry, Pharmaceutical Science, Absolute Configuration +15

Structure–activity relationships of the oxindole growth hormone secretagogues

Teruhisa Tokunaga, W. Ewan Hume, Jun Nagamine et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 136 citations · Full text

Growth Hormone, Biochemistry, Endocrine Mechanism +5

Palladium‐Catalysed Intramolecular Cyclisations of Olefinic Propargylic Carbonates and application to the diastereoselective synthesis of enantiomerically pure (−)‐α‐thujone

Wolfgang Oppolzer, Austen D. Pimm, Blanda Stammen et al. · Helvetica Chimica Acta · 1997 · 93 citations · Full text

Engineering, Natural Sciences, Diversity-oriented Synthesis +13

Quantitative Evaluation of mMate1 Function Based on Minimally Invasive Measurement of Tissue Concentration Using PET with [11C]Metformin in Mouse

Tomotaka Shingaki, W. Ewan Hume, Tadayuki Takashima et al. · Pharmaceutical Research · 2015 · 39 citations

Animal Physiology, Positron Emission Tomography, Molecular Physiology +10

The synthesis and biodistribution of [11C]metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1) in vivo

W. Ewan Hume, Tomotaka Shingaki, Tadayuki Takashima et al. · Bioorganic & Medicinal Chemistry · 2013 · 37 citations · Full text

Pet Probe, Biochemistry, Hepatobiliary Transport +4