Jody Freeman

Preclinical pharmacology of the α4β2 nAChR partial agonist varenicline related to effects on reward, mood and cognition

Hans Rollema, Mihály Hajós, Patricia A. Seymour et al. · Biochemical Pharmacology · 2009 · 116 citations

Medicine, Neuroscience, Pharmacology +10

Discovery of Two Clinical Histamine H ₃ Receptor Antagonists: <i>trans</i> - <i>N</i> -Ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and <i>trans</i> -3-Fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]- <i>N</i> -(2-methylpropyl)cyclobutanecarboxamide (PF-03654764)

Travis T. Wager, Betty Pettersen, Anne W. Schmidt et al. · Journal of Medicinal Chemistry · 2011 · 108 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Phosphodiesterase 9A Regulates Central cGMP and Modulates Responses to Cholinergic and Monoaminergic Perturbation In Vivo

Robin J. Kleiman, Douglas S. Chapin, Curt Christoffersen et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 80 citations

Life Sciences, Neuroscience, Pharmacology +17

2-Aryloxy-4-alkylaminopyridines: Discovery of Novel Corticotropin-Releasing Factor 1 Antagonists

Yuhpyng L. Chen, R. Scott Obach, John P. Braselton et al. · Journal of Medicinal Chemistry · 2008 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8